Related Experiment Video
Updated: Jul 8, 2026

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program
Published on: April 19, 2019
Influence of physical training on cardiac performance in patients with coronary artery disease and exercise-induced
Iwona Korzeniowska-Kubacka1, Maria Bilińska, Ryszard Piotrowicz
1Department of Cardiac Rehabilitation and Noninvasive Electrocardiology, National Institute of Cardiology, Warsaw, Poland. drkubacka@wp.pl
Objective:
The aim of the study was to assess the influence of physical training on systolic and diastolic left ventricular (LV) function using seismocardiography (SCG) and its relationship to the exercise capacity in CAD patients with exercise-induced LV dysfunction.
Methods And Results:
Eighty men aged 52.5 +/- 7.5 y with stable CAD were assigned to either a control group (CG, n = 40) or a training group (TG, n = 40).TG patients underwent a 4.5-month training programme (TP). Before and at the end of the study all patients underwent a cardiopulmonary test (CPET) and SCG. After TP the following CPET parameters improved significantly: duration (776 +/-120 vs. 879 +/- 89 s, P<0.001), METs (8 +/- 2 vs. 10 +/- 1, P<0.01), maxVO2 (22 +/- 4 vs. 25 +/- 3 ml/kg/min, P < 0.001). During SCG performed before (SCG(REST)) and immediately after each CPET (SCG(CPET)) the following variables improved significantly, but only in TG patients: the pre-ejection period (PEP; 126 +/- 15 vs. 119 +/- 14, P < 0.05 ms), PEP/LVET ratio (PEP/LV ejection time, ms; 0.42 +/- 0.08 vs. 0.38 +/- 0.06, P < 0.05). There was a negative correlation between training-induced changes in maxVO2 and PEP(CPET) (r =-0.4, P = 0.01) and PEP/LVET(CPET) (r =-0.52, P = 0.001), and a positive correlation between maxVO2 and LVET(CPET) (r = 0.51, P = 0.01). After TP, there was also a negative correlation between maxVO2 and isovolumetric relaxation time (ms; r =-0.46, P = 0.01).
Conclusions:
The training programme resulted in a significant improvement in the physical capacity and cardiac performance in CAD patients with exercise-induced left ventricular dysfunction. An improvement of systolic left ventricular function suggested an increase in exercise capacity.
Related Concept Videos
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Exercise and Cardiac Output
Sustained exercise increases the muscles' oxygen demand, which can be met...
Pathophysiology of Cardiac Performance
Imbalances in Cardiac Output
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Cardiomyopathy V: Interprofessional Care
