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Inducing Apical Periodontitis in Mice
Published on: August 6, 2019
Ameloblastoma suggesting large apical periodontitis
Luiz Augusto Faitaroni1, Mike Reis Bueno, Artur Aburad De Carvalhosa
1Dentistry Brazilian Association, Goiânia, GO, Brazil.
Journal of Endodontics
|January 25, 2008
Summary
A rare case of ameloblastoma mimicked a large apical periodontitis, requiring surgical removal and histopathologic examination for definitive diagnosis. This highlights the importance of considering ameloblastoma in endodontic differential diagnoses for periapical lesions.
Area of Science:
- Dentistry
- Oral Pathology
- Oncology
Background:
- Apical periodontitis can present as a large lesion with well-defined margins.
- Endodontic treatment is the standard approach for apical periodontitis.
- Odontogenic neoplasms can sometimes mimic inflammatory periapical lesions.
Observation:
- A large apical periodontitis adjacent to teeth #22-24 was treated endodontically.
- Post-treatment, continued expansion of the mandible cortical bone was observed.
- Surgical enucleation of the lesion was performed for histopathologic examination.
Findings:
- Microscopic examination revealed the lesion to be an ameloblastoma.
- Ameloblastoma, a benign epithelial neoplasm of odontogenic origin, can present as a periapical lesion.
- Histopathologic examination is crucial for definitive diagnosis of certain periapical lesions.
Implications:
- Ameloblastoma should be included in the differential diagnosis of periapical lesions.
- Histopathologic examination is essential for accurate diagnosis when endodontic treatment fails or bone expansion occurs.
- This case underscores the importance of a multidisciplinary approach in managing complex oral lesions.

