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Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

Race and sex differences in hypertension control in CKD: results from the Kidney Early Evaluation Program (KEEP)

Obidiugwu Kenrik Duru1, Suying Li, Claudine Jurkovitz

  • 1Division of General Internal Medicine/Health Services Research, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA. kduru@mednet.ucla.edu

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
|January 25, 2008
PubMed

Insights

African American men with chronic kidney disease (CKD) experience worse hypertension control than other groups, especially in early stages. Addressing this disparity is crucial for slowing CKD progression to end-stage renal disease.

Area of Science:

  • Nephrology
  • Cardiovascular Health
  • Health Disparities

Background:

  • African American men with chronic kidney disease (CKD) face more rapid progression to end-stage renal disease compared to other demographics.
  • Hypertension is a key factor exacerbating CKD, and disparities in its management may drive these unequal outcomes.

Purpose of the Study:

  • To investigate hypertension control rates among African American men with CKD in comparison to women and white individuals.
  • To identify potential race and sex disparities in hypertension management within the CKD population.

Main Methods:

  • A cross-sectional study analyzed data from 10,827 individuals with CKD and hypertension from the Kidney Early Evaluation Program.
  • Predictors examined included African American race and sex.
  • Hypertension control was defined as blood pressure below 130/80 mm Hg, assessed via physical examination and laboratory data.

Main Results:

  • In early-stage CKD, African American women, white men, and white women had significantly higher odds of controlled hypertension compared to African American men.
  • In late-stage CKD, white men and white women also showed greater odds of hypertension control than African American men.
  • No significant differences in hypertension control were observed between African American men and women in the late stages of CKD.

Conclusions:

  • African American men with CKD exhibit poorer hypertension control, particularly in the early disease stages, compared to other demographic groups.
  • Targeted interventions to aggressively manage hypertension in African American men with CKD are recommended to reduce disparities in progression to end-stage renal disease.
Abstract

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