Primary monophasic synovial sarcoma presenting as a pulmonary mass: a case report

Area of Science:

• Oncology
• Pulmonology
• Pathology

Background:

• Primary pulmonary synovial sarcoma is an exceedingly rare thoracic malignancy.
• Few documented cases exist in medical literature, highlighting its rarity.

Purpose of the Study:

• To present a case of monophasic primary pulmonary synovial sarcoma.
• To emphasize the diagnostic challenges and treatment considerations for this rare tumor.

Main Methods:

• A 67-year-old female patient presented with a pulmonary mass detected on routine X-ray.
• Diagnostic work-up included thoracic computed tomography (CT) and exclusion of metastatic disease.
• Surgical resection of the affected lung lobe (lobectomy) was performed for diagnosis and treatment.

Main Results:

• Thoracic CT revealed a soft-tissue mass in the left lower lobe, near the pleura.
• No suspicious lymph nodes or signs of metastasis were identified.
• Histopathological examination confirmed the diagnosis of monophasic synovial sarcoma.

Conclusions:

• Diagnosing primary pulmonary synovial sarcoma requires a comprehensive approach, integrating clinical, imaging, and immunohistochemical findings.
• Surgical excision, such as lobectomy or pneumonectomy, is the preferred treatment and aids in diagnosis.
• The overall prognosis for primary pulmonary synovial sarcoma remains poor.