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Updated: Jul 8, 2026

Echocardiographic Assessment of Cardiac Anatomy and Function in Adult Rats
Published on: December 13, 2019
Assessment of left ventricular ejection fraction from technetium-99m-methoxy isobutyl isonitrile multiple-gated
M H Davis1, B Rezaie, F L Weiland
1Dept. of Electr. Eng., St. Mary's Univ., San Antonio, TX.
Abstract:
Abnormal left ventricular function is a diagnostic indication of cardiac disease. Left ventricular function is commonly quantified by ejection fraction measurements. A novel approach for the determination of left ventricular ejection fraction from technetium-99m-methoxy isobutyl isonitrile multiple-gated radionuclide angiocardiography is presented. Data from 23 patients, symptomatic of cardiac disease, indicate that ejection fractions determined using the radionuclide technique correlate well with contrast X-ray single-plane cineangiography (r=0.83, p<10(-6)). Data from 14 of the patients indicate favorable correlation with technetium-99m-pertechnetate gated blood pool radionuclide angiocardiography (r=0.87, p<10(-4)).
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