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Updated: Jul 8, 2026

A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space
Published on: February 1, 2016
On the relation between the ISRA and the EM algorithm for positron emission tomography
1Inst. de Matematica Estatistica, e Ciencia da Computacao, Univ. Estadual de Campinas, Sao Paulo.
Abstract:
The image space reconstruction algorithm (ISRA) was proposed as a modification of the expectation maximization (EM) algorithm based on physical considerations for application in volume emission computered tomography. As a consequence of this modification, ISRA searches for least squares solutions instead of maximizing Poisson likelihoods as the EM algorithm. It is shown that both algorithms may be obtained from a common mathematical framework. This fact is used to extend ISRA for penalized likelihood estimates.
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