Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Colour and photosensitive epilepsy.

J C Mesri1, C Dellepiane

  • 1Sección Neurofisiológica, Hospital Juan A. Fernández, Buenos Aires.

Medicina
|January 1, 1991
PubMed
Summary

Blue filters significantly reduce or block photoconvulsive responses (PR) in photosensitive epilepsy patients. This suggests the retina plays a key role in triggering these seizure-like events.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Erratum to 'Evaluation of COVID-19 impact on DELAYing diagnostic-therapeutic pathways of lung cancer patients in Italy (COVID-DELAY study): fewer cases and higher stages from a real-world scenario': [ESMO Open Volume 7, Issue 2, April 2022, 100406].

ESMO open·2022
Same author

Evaluation of COVID-19 impact on DELAYing diagnostic-therapeutic pathways of lung cancer patients in Italy (COVID-DELAY study): fewer cases and higher stages from a real-world scenario.

ESMO open·2022
Same author

Stereotypies in Wilson's disease.

Movement disorders : official journal of the Movement Disorder Society·1997
Same author

Reading epilepsy.

Epilepsia·1987

Area of Science:

  • Neurology
  • Ophthalmology
  • Biophysics

Background:

  • Photosensitive epilepsy (PSE) is a neurological condition characterized by seizures triggered by visual stimuli.
  • The photoconvulsive response (PR) is a common EEG finding in PSE, involving abnormal electrical activity in the brain.
  • Understanding the mechanisms underlying PR is crucial for developing effective management strategies.

Purpose of the Study:

  • To investigate the effect of different colored filters on the photoconvulsive response in patients with photosensitive epilepsy.
  • To explore the role of the retina in the genesis of the photoconvulsive response.

Main Methods:

  • Seven patients with photosensitive epilepsy were studied using an 8-channel electroencephalograph.
  • Patients were stimulated with a Joule lamp at frequencies from 1 to 30 flashes per second.
  • Red, yellow, blue, and green cellophane filters were used to modulate the light stimulus.

Main Results:

  • The blue filter significantly delayed the onset of the PR (average 6 seconds after eye closure) and reduced its amplitude.
  • A double blue filter completely blocked the PR in some instances.
  • EEG recordings showed bilateral spikes, polyspikes, and slow wave paroxysmal discharges, modulated by filter color.

Conclusions:

  • The findings strongly support the involvement of the retina in the generation of the photoconvulsive response.
  • Blue filters appear to limit light transmission to a level insufficient to trigger the PR, suggesting a threshold mechanism.
  • Further research into light filtering could offer novel therapeutic approaches for photosensitive epilepsy.

Related Experiment Videos