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Published on: September 19, 2015
The identification of children with cleft palate and sleep disordered breathing using a referral system
J E MacLean1, D Fitzsimons, P Hayward
1Department of Respiratory Medicine, The Children's Hospital at Westmead, Westmead, New South Wales, Australia. joannam4@med.usyd.edu.au
Insights
Children with cleft palate have a high risk of sleep disordered breathing (SDB). Surgical status, particularly before palatoplasty, is linked to more severe SDB in these children.
Area of Science:
- Pediatric Pulmonology
- Craniofacial Anomalies
- Sleep Medicine
Background:
- Cleft palate increases the risk of sleep disordered breathing (SDB), but the extent and specific risk factors remain unclear.
- Early identification of SDB in children with cleft palate is crucial for timely intervention.
Purpose of the Study:
- To characterize the clinical features and sleep study outcomes in children with cleft palate.
- To identify potential risk factors associated with SDB in this patient group.
Main Methods:
- Retrospective chart review of sleep study results and clinical data from children with cleft palate.
- Analysis of clinical features including age, gender, syndrome diagnosis, cleft classification, and surgical status.
Main Results:
- 87% of children with cleft palate exhibited SDB, with 28% having severe SDB.
- Surgical status was significantly associated with SDB severity, with pre-palatoplasty/pharyngoplasty linked to more severe SDB.
Conclusions:
- Children with cleft palate face a substantial risk of SDB.
- Further prospective studies are required to fully define SDB risk characteristics and key factors in this population.
Background:
Cleft palate is associated with an increased risk of sleep disordered breathing (SDB) but the magnitude of this risk and specific risk factors are unclear. A better understanding of these components of risk will aid the early identification of SDB in this group of children.
Objective:
To describe the clinical characteristics and results of sleep studies undertaken in a cohort of children with cleft palate. Clinical features will be examined to determine potential associations with SDB in this group.
Method:
A retrospective chart review was undertaken to ascertain sleep study results and clinical data for all children with cleft palate. Clinical features of interest included age, gender, syndrome diagnosis, cleft classification, and surgical status.
Results:
A total of 99 sleep studies were available from 62 children. The sample included a select group of children with cleft palate with features predictive of a high risk of SDB. Baseline sleep study results were consistent with SDB for 87% of children and 28% (15 of 54) of these children demonstrated severe SDB. Uni-variate analysis showed that age, syndrome, and surgical status had significant association with the severity of SDB. On multi-variate analysis only surgical status maintained this association, such that pre-palatoplasty/pharyngoplasty was associated with more severe SDB. Follow-up studies were completed in one-third of the cohort.
Conclusion:
Children with cleft palate appear to have a significant risk of SDB. A prospective study of a population of children with cleft palate is needed to further define the characteristics of this risk and important risk factors.
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