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Related Experiment Video

Updated: Jul 8, 2026

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice
08:50

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice

Published on: October 18, 2024

Duodenal switch: long-term results.

Picard Marceau1, Simon Biron, Frédéric-Simon Hould

  • 1Department of Surgery, Laval University, Laval Hospital, Québec, Canada. picard.marceau@chg.ulaval.ca

Obesity Surgery
|January 26, 2008
PubMed
Summary
This summary is machine-generated.

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Duodenal switch (DS) surgery is highly effective for long-term morbid obesity treatment, with significant improvements in comorbidities and patient satisfaction. This bariatric procedure demonstrates a favorable risk-benefit profile with proper follow-up.

Area of Science:

  • Bariatric Surgery
  • Surgical Innovation
  • Obesity Management

Background:

  • This study details 15-year outcomes of duodenal switch (DS) as a primary bariatric procedure.
  • Data encompasses 1,423 patients operated on between 1992 and 2005.

Purpose of the Study:

  • To evaluate the long-term efficacy and safety of duodenal switch surgery.
  • To assess the impact of DS on morbid obesity and associated comorbidities.

Main Methods:

  • A retrospective analysis of 1,423 patients undergoing duodenal switch.
  • High follow-up rate (97%) including clinical and biochemical evaluations.

Main Results:

  • 92% survival rate post-DS; operative mortality at 1% comparable to gastric bypass.

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Single-Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy Model in Mice
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Last Updated: Jul 8, 2026

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice
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Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice

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Single-Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy Model in Mice
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Single-Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy Model in Mice

Published on: February 10, 2023

  • Significant BMI reduction: 92% achieved BMI < 35 (initial BMI ≤ 50), 83% achieved BMI < 40 (initial BMI > 50).
  • High comorbidity resolution rates: 92% diabetes cure, 90% CPAP discontinuation, 88% asthma medication reduction, 86% decrease in cardiac risk index.

    • Conclusions:

    • Duodenal switch is a highly effective long-term solution for morbid obesity and its comorbidities.
    • The procedure offers a favorable risk-benefit ratio when combined with appropriate follow-up.
    • Patient satisfaction with weight loss and overall results is notably high (95%).