Related Experiment Videos
Overcoming barriers to evidence-based diabetes care
Richard W Grant1, James B Meigs
1General Medicine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. Rgrant@partners.org
Current Diabetes Reviews
|January 29, 2008
Summary
Despite guidelines, diabetes patients face complications due to poor translation of evidence into practice. Key barriers include medication adherence, lack of treatment adjustment, and system limitations, impacting diabetes management.
Area of Science:
- Endocrinology and Metabolism
- Cardiovascular Disease
- Health Services Research
Background:
- Diabetes patients experience high rates of cardiovascular and microvascular complications, leading to a significant lifespan reduction.
- Effective translation of evidence-based guidelines into routine diabetes care remains a major challenge.
- Diabetes management involves complex interactions between patients, providers, and healthcare systems.
Purpose of the Study:
- To review current evidence on barriers hindering effective diabetes care.
- To identify factors contributing to the gap between clinical evidence and practice.
- To explore potential solutions for improving diabetes outcomes.
Main Methods:
- Review of existing literature on diabetes care barriers.
- Analysis of factors influencing medication adherence and treatment adjustments.
- Examination of healthcare system limitations in managing chronic diseases.
- Evaluation of informatics-based interventions for diabetes care.
Main Results:
- Complex medication regimens (polypharmacy) pose challenges to patient adherence.
- Inadequate adjustment of medications for patients exceeding risk factor goals is prevalent.
- Current healthcare systems struggle to effectively manage complex chronic conditions like diabetes.
- Population-level, informatics-based interventions show promise in improving diabetes care.
Conclusions:
- Addressing medication adherence, optimizing treatment adjustments, and improving healthcare system organization are crucial for better diabetes outcomes.
- Informatics-based strategies offer a potential pathway to enhance the delivery of evidence-based diabetes care.
- Bridging the gap between evidence and practice is essential to reduce the burden of diabetes complications.
Related Concept Videos
Diabetes: Management and Pharmacotherapy
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Type II Diabetes I: Introduction
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...
Diabetes Mellitus: Overview and Type I Subtype
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Diabetes: Symptoms, Diagnosis, and Complications
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is based on...
Diabetes Mellitus: Type 2 and Gestational
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
Diabetes Mellitus: Introduction
Diabetes mellitus consists of chronic metabolic disorders characterized by persistent hyperglycemia. This elevated blood glucose results from defects in insulin secretion, impaired insulin action, or both. Insulin, produced by pancreatic β-cells, is essential for maintaining glucose homeostasis by facilitating cellular glucose uptake for energy or storage. Disruptions in insulin production or function lead to glucose accumulation in the bloodstream, causing the clinical features and long-term...