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Laparoscopic versus open partial nephrectomy: analysis of the current literature
Francesco Porpiglia1, Alessandro Volpe, Michele Billia
1Department of Urology, San Luigi Hospital, Orbassano, University of Turin, Turin, Italy. porpiglia@libero.it <porpiglia@libero.it>
European Urology
|January 29, 2008
Summary
Open partial nephrectomy (OPN) remains the primary treatment for small renal tumors. Laparoscopic partial nephrectomy (LPN) shows comparable outcomes in experienced centers but requires careful case selection and further study.
Area of Science:
- Urology
- Surgical Oncology
Background:
- Renal tumors are a significant clinical concern.
- Surgical management options include open partial nephrectomy (OPN) and laparoscopic partial nephrectomy (LPN).
Purpose of the Study:
- To critically review the scientific evidence comparing OPN and LPN for renal tumors.
- To define the current role of OPN and LPN in treating renal tumors.
Main Methods:
- A comprehensive literature search of PubMed and Medline databases.
- Review of reports on OPN and LPN published between 1990 and 2007.
Main Results:
- OPN is an established curative treatment for small renal tumors.
- LPN demonstrates similar intermediate-term oncologic and functional outcomes to OPN in experienced centers.
- LPN presents challenges, including longer ischemia times and a steep learning curve, necessitating careful case selection.
Conclusions:
- OPN is currently the preferred treatment for small renal tumors.
- LPN is technically demanding but offers comparable oncologic and functional results in specialized centers.
- Further research, including prospective randomized trials, is needed to validate LPN's long-term safety and efficacy.

