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Published on: March 6, 2018
What Comes After Matters: The Importance of Postprogression Care in Patients with Metastatic Hormone-sensitive
Ashkan Mortezavi1, Tom van der Hulle2, Roderick van den Bergh3
1Department of Urology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
European Urology
|July 23, 2026
Abstract:
Upfront combination therapy in mHSPC improves outcomes; however, without guaranteed postprogression therapy in control arms, survival benefits may partly reflect undertreatment in the control groups rather than true superiority. Trial designs incorporating planned treatment sequencing are needed to support rational deescalation strategies.
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