Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Evolution of alpha satellite.

H F Willard1

  • 1Department of Genetics, Stanford University, California 94305.

Current Opinion in Genetics & Development
|December 1, 1991
PubMed
Summary
This summary is machine-generated.

Alpha satellite DNA is a key model for studying repetitive DNA evolution. This review covers recent advances in primate alpha satellite structure and evolution, highlighting its importance in understanding multigene families.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of delivery models on understanding genomic risk for type 2 diabetes.

Public health genomics·2014
Same author

Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant.

Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology·2013
Same author

Pulsed-field and two-dimensional gel electrophoresis of long arrays of tandemly repeated DNA : analysis of human centromeric alpha satellite.

Methods in molecular biology (Clifton, N.J.)·2011
Same author

Sequence organization and functional annotation of human centromeres.

Cold Spring Harbor symposia on quantitative biology·2004
Same author

You say tomato and I say tomahto: human genetics and gene therapy.

Molecular therapy : the journal of the American Society of Gene Therapy·2001
Same author

Genomic and genetic definition of a functional human centromere.

Science (New York, N.Y.)·2001
Same journal

Temporal trajectories underlying adult neuronal diversity.

Current opinion in genetics & development·2026
Same journal

Transcription regulation of cell fate plasticity - from embryonic development to tissue regeneration.

Current opinion in genetics & development·2026
Same journal

Shared molecular and cellular programs during regeneration of glandular epithelia.

Current opinion in genetics & development·2026
Same journal

Lineage tracing in human cortical development.

Current opinion in genetics & development·2026
Same journal

Cis-regulatory strategies in developmental patterning.

Current opinion in genetics & development·2026
Same journal

GABAergic neuron fate specification and lineage allocation: from development to disorder.

Current opinion in genetics & development·2026
See all related articles

Area of Science:

  • Genomics
  • Molecular Biology
  • Evolutionary Biology

Background:

  • Alpha satellite DNA represents a well-studied family of repetitive DNA.
  • It serves as a fundamental model for comprehending other satellite DNA and multigene families.
  • Satellite DNA plays crucial roles in chromosome structure and function.

Purpose of the Study:

  • To review recent advancements in the understanding of human and primate alpha satellite DNA.
  • To elucidate the evolutionary mechanisms, including intra- and interchromosomal processes, governing alpha satellite DNA.
  • To provide a comprehensive overview of the current state of research on alpha satellite DNA structure and evolution.

Main Methods:

  • Literature review of recent studies on primate alpha satellite DNA.

Related Experiment Videos

  • Comparative genomic analysis of alpha satellite sequences across primate species.
  • Bioinformatic tools for analyzing repetitive DNA structures and evolutionary patterns.

    • Main Results:

    • Alpha satellite DNA exhibits complex structures and dynamic evolutionary histories within primate genomes.
    • Both intragenomic (intrachromosomal) and intergenomic (interchromosomal) mechanisms contribute significantly to its evolution.
    • Specific sequence features and repeat arrays are conserved or diverge across primate lineages, reflecting distinct evolutionary trajectories.

    Conclusions:

    • Alpha satellite DNA evolution is shaped by a combination of concerted evolution and other forces.
    • Understanding primate alpha satellite DNA provides insights into genome evolution and the dynamics of repetitive elements.
    • This review synthesizes current knowledge, setting the stage for future research into satellite DNA biology.