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Updated: Jul 7, 2026

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
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From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

Published on: January 13, 2017

A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic

Jian Zhang1, Steven G Van Lanen, Jianhua Ju

  • 1Department of Chemistry, Division of Pharmaceutical Sciences, and University of Wisconsin National Cooperative Drug Discovery Group, University of Wisconsin, Madison, WI 53705, USA.

Proceedings of the National Academy of Sciences of the United States of America
|January 29, 2008
PubMed

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