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From causal diagrams to birth weight-specific curves of infant mortality
Sonia Hernández-Díaz1, Allen J Wilcox, Enrique F Schisterman
1Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA. shernan@hsph.harvard.edu
Abstract:
This report explores the low birth weight paradox using two graphical approaches: causal directed acyclic graphs (DAGs), and the empirical curves of the birth weight distribution and birth weight-specific mortality. The birth weight curves are able to represent the associations quantitatively, while the corresponding causal DAGs provide a set of plausible explanations for the findings. Taken together, these two approaches can facilitate discussion of underlying biological mechanisms.
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