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Analyzing and Building Nucleic Acid Structures with 3DNA
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Analyzing and Building Nucleic Acid Structures with 3DNA

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Compressed indexing and local alignment of DNA.

T W Lam1, W K Sung, S L Tam

  • 1Department of Computer Science, University of Hong Kong, Hong Kong, China. twlam@cs.hku.hk

Bioinformatics (Oxford, England)
|January 30, 2008
PubMed
Summary

This study introduces BWT-SW, a tool that uses Burrows-Wheeler Transform (BWT) indexes to efficiently find all local alignments in large biological sequences. BWT-SW significantly speeds up alignment discovery compared to traditional methods, aiding genomic research.

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