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Published on: July 21, 2023
Obscure gastrointestinal bleeding: evaluation with 64-section multiphase CT enterography--initial experience
James E Huprich1, Joel G Fletcher, Jeffrey A Alexander
1Department of Radiology, Mayo Clinic, 200 First Ave SW, Rochester, MN 55905, USA. huprich@mayo.edu
Insights
Computed tomographic (CT) enterography effectively identifies bleeding sources in obscure gastrointestinal bleeding (OGIB). This imaging technique aids in detecting lesions missed by capsule endoscopy, improving diagnostic accuracy for OGIB.
Area of Science:
- Radiology
- Gastroenterology
Background:
- Obscure gastrointestinal bleeding (OGIB) presents a diagnostic challenge.
- Conventional endoscopic methods may not always identify the bleeding source.
Purpose of the Study:
- To retrospectively evaluate computed tomographic (CT) enterography for diagnosing OGIB.
- To assess the utility of a 64-section CT system with neutral enteric contrast and three-phase acquisition.
Main Methods:
- Retrospective analysis of 22 patients with OGIB who underwent CT enterography.
- Comparison of CT enterography findings with capsule endoscopy, traditional endoscopy, surgery, and angiography.
- Utilized a 64-section CT system with neutral enteric contrast and a three-phase acquisition protocol.
Main Results:
- CT enterography identified a bleeding source in 10 out of 22 patients (45%).
- Eight of these positive findings correlated with capsule endoscopy or clinical diagnosis.
- CT enterography detected three lesions missed by capsule endoscopy.
Conclusions:
- Multiphase, multiplanar CT enterography shows promise in evaluating OGIB.
- CT enterography can be a valuable tool for identifying gastrointestinal bleeding sources.
- This technique may improve diagnostic yield in challenging OGIB cases.
Abstract:
This retrospective HIPAA-compliant study was approved by the institutional review board and institutional conflict of interest committee. Patients gave informed consent for use of medical records. The purpose of the study was to retrospectively evaluate the findings depicted at computed tomographic (CT) enterography performed with a 64-section CT system and by using neutral enteric contrast material and a three-phase acquisition in patients with obscure gastrointestinal bleeding (OGIB). Twenty-two outpatients (11 men, 11 women; age range, 37-83 years) with OGIB underwent CT enterography. Findings were compared with capsule and traditional endoscopic, surgical, and angiographic findings. CT enterographic findings were positive for a bleeding source in 10 (45%) of 22 patients. Eight of 10 positive findings at CT enterography were also positive at capsule endoscopy or subsequent clinical diagnosis. CT enterography helped correctly identify three lesions undetected at capsule endoscopy. Study results suggest that multiphase, multiplanar CT enterography may have a role in the evaluation of OGIB.
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