Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Determination of Crystal Structures

Determination of Crystal Structures

In the late 1800s, the revelation that light extended beyond visible wavelengths led to the discovery of X-rays by Wilhelm Roentgen. Recognized as high-energy electromagnetic radiation with short wavelengths, X-rays prompted exploration into their interaction with crystals. Max von Laue proposed in 1912 that the periodic arrangement of atoms, ions, or molecules in crystals would cause them to diffract X-rays, a hypothesis confirmed through experiments with copper sulfate and zinc sulfide...

Positron Emission Tomography

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A 6-month randomized, double-blind, placebo-controlled trial of weekly exenatide in adolescents with obesity.

Pediatric obesity·2020

Same author

SU-E-I-82: Image Signal-To-Noise Equalization in Whole Body PET Using Variable Acquisition Times.

Medical physics·2017

Same author

TU-E-218-01: PET/CT QA/QC and Acceptance Testing.

Medical physics·2017

Same author

SU-E-J-169: 4D-PET for Abdominal Tumor Target Volume Generation.

Medical physics·2017

Same author

WE-G-213CD-02: 4D-PET Maximum Intensity Projections Improve Accuracy of Mobile Tumor Volume Delineation.

Medical physics·2017

Same author

Urban runoff as a source of polycyclic aromatic hydrocarbons to coastal waters.

Environmental science & technology·2012

Search research articles

Related Experiment Video

Updated: Jul 7, 2026

A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space

A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space

Published on: February 1, 2016

An evaluation of a two-dimensional array detector for high resolution PET.

M Dahlbom¹, E J Hoffman

¹Sch. of Med., California Univ., Los Angeles, CA.

IEEE Transactions on Medical Imaging

|January 1, 1988

Summary

This study evaluated a bismuth germanate (BGO) detector system for positron emission tomography. Energy discrimination significantly improved crystal identification and spatial resolution, achieving up to 87% accuracy.

More Related Videos

Automated Rat Single-Pellet Reaching with 3-Dimensional Reconstruction of Paw and Digit Trajectories

Automated Rat Single-Pellet Reaching with 3-Dimensional Reconstruction of Paw and Digit Trajectories

Published on: July 10, 2019

Dual Raster-Scanning Photoacoustic Small-Animal Imager for Vascular Visualization

Dual Raster-Scanning Photoacoustic Small-Animal Imager for Vascular Visualization

Published on: July 15, 2020

Related Experiment Videos

Last Updated: Jul 7, 2026

A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space

A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space

Published on: February 1, 2016

Automated Rat Single-Pellet Reaching with 3-Dimensional Reconstruction of Paw and Digit Trajectories

Automated Rat Single-Pellet Reaching with 3-Dimensional Reconstruction of Paw and Digit Trajectories

Published on: July 10, 2019

Dual Raster-Scanning Photoacoustic Small-Animal Imager for Vascular Visualization

Dual Raster-Scanning Photoacoustic Small-Animal Imager for Vascular Visualization

Published on: July 15, 2020

Area of Science:

Nuclear Instrumentation
Medical Imaging Physics

Background:

Positron Emission Tomography (PET) imaging relies on accurate detector systems.
Bismuth germanate (BGO) crystals are commonly used in PET detectors due to their high light output and density.

Purpose of the Study:

To evaluate the performance of a 2D array detector system composed of BGO crystals.
To assess the detector's coincidence timing resolution, energy resolution, and crystal identification capabilities.

Main Methods:

A detector system with 4x8 matrices of BGO crystals coupled to four photomultipliers was constructed and tested.
Coincidence timing resolution and energy resolution were measured.
A signal processing method involving pairwise summing and subtraction was used to identify detector elements.
The impact of energy discrimination on crystal identification was investigated.

Main Results:

Coincidence timing resolution was measured at 6.1 ns FWHM and 11.3 ns FWTM.
Energy resolution per crystal ranged from 16.8% to 24.1% FWHM at 511 keV.
Detector identification accuracy varied from 76% to 87% across six tested conditions.
Energy discrimination was identified as the most critical factor for improving crystal identification and spatial resolution.

Conclusions:

The evaluated 2D BGO array detector system demonstrates promising performance for PET imaging.
Optimized signal processing and energy discrimination are crucial for achieving high spatial resolution and accurate event localization.
Further development could enhance the system's capabilities for clinical applications.