Related Experiment Video
Updated: Jul 7, 2026

Robot-Assisted Laparoscopic Splenectomy In Children: A Case Report with Literature Review
Published on: March 27, 2026
[Clinical features of sideropenic anemias in infants and small children]
1Pedijatrijska klinika, Klinicki centar Univerziteta u Sarajevu.
Insights
Iron-deficiency anemia (IDA) is common in children. Key clinical signs like paleness, dry skin, and brittle hair indicate IDA severity, guiding treatment for this frequent childhood anemia.
Area of Science:
- Pediatrics
- Hematology
- Nutritional Science
Context:
- Iron-deficiency anemia (IDA) is the most prevalent anemia globally in childhood.
- Early identification of IDA is crucial for appropriate management and preventing long-term complications.
Purpose:
- To delineate the primary clinical manifestations of iron-deficiency anemia (IDA) in infants and young children.
- To correlate specific clinical signs with varying degrees of anemia severity based on hemoglobin levels.
Summary:
- A retrospective study analyzed anemic children (Hb < 110 g/l) and a control group (Hb > 110 g/l) aged 6-24 months.
- Universal findings included paleness; statistically significant differences were observed in dry, scaly skin (p=0.006) and brittle, light hair (p=0.003) in severe IDA (Hb < 95 g/l).
- No significant growth retardation was noted between groups, suggesting localized clinical signs are key indicators.
Impact:
- Clinical features of IDA, alongside hemoglobin levels, are pivotal in determining anemia severity.
- This information guides therapeutic strategies and treatment directions for iron-deficiency anemia in pediatric populations.
- Highlights the importance of recognizing specific physical signs for early diagnosis and intervention in pediatric IDA.
Unlabelled:
The aim of the paper is to present the main clinical features of iron-deficiency anemia (IDA) in infants and in small children. IDA is the most frequent anemia in childhood word-wide. In retrospective study we explore go anemic children with Hb < 110 g/l and 30 children with Hb > 110 g/l, aged 6-24 months.
Results:
Paleness of the skin and visible mucosa was present in all children (100%). Presence of of dry and scaly skin was statistically different (p = 0.006) between group with Hb < 95 g/l and control group. Breakable and light hair was statistically significantly frequent (p = 0.003) in children with severe form of anemia (Hb < 95 g/l) than in dose with mild anemia (Hb 95-110 g/l). High statistically significant difference (Hb 95-110 g/l) was present between group with Hb < 95 g/l and control group (Hb > 110 g/l). There was no statistically significant (p > 0.05) growth retardation between explored groups.
Conclusion:
clinical features of IDA and hemoglobin level determine severity and treatment directions of IDA.
More Related Videos
Related Concept Videos
Disorders of Erythrocytes
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Pharmacokinetics in Pediatric Patients: Drug Metabolism
Overview of Hematopoiesis
Developmental Phases of Hematopoiesis
Initially, HSCs are formed in the embryonic yolk sac, a critical site for early blood cell production. These stem cells subsequently migrate to other...
Erythropoiesis
Inborn Errors of Metabolism

