Related Experiment Video
Updated: Jul 7, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
Infant intraosseous infusion
Scott DeBoer1, Terri Russell, Michael Seaver
1University of Chicago Hospitals, USA. scott@peds-r-us.com
Intraosseous (IO) infusion offers a critical alternative when intravenous (IV) access is difficult in newborns. This method provides rapid fluid and medication delivery for critically ill infants when other vascular access fails.
Area of Science:
- Neonatal Medicine
- Pediatric Critical Care
- Emergency Medicine
Background:
- Umbilical cord access is common for neonates but often unavailable after the immediate newborn period.
- Peripheral intravenous (IV) access can be challenging to establish in critically ill newborns.
- Intraosseous (IO) infusion is an underutilized but effective alternative vascular access method in neonates.
Purpose of the Study:
- To review the utility of intraosseous (IO) infusion in neonatal care.
- To describe available IO infusion devices and optimal placement sites for infants.
- To outline the assessment and management of neonates receiving IO therapy.
Main Methods:
- Literature review of intraosseous (IO) infusion in neonatal populations.
- Analysis of IO device technology and anatomical considerations for neonatal placement.
- Discussion of clinical protocols for IO fluid and medication administration in neonates.
Main Results:
- IO infusion provides rapid and reliable vascular access when IV access is not feasible in neonates.
- Various IO devices are available, with specific sites recommended for neonatal anatomy.
- Careful monitoring and management are essential for infants receiving IO infusions.
Conclusions:
- Intraosseous (IO) infusion is a valuable and viable resuscitation tool for critically ill neonates.
- Healthcare providers should be familiar with IO techniques for timely vascular access.
- Expanding the use of IO infusion can improve outcomes for neonates requiring urgent vascular access.
Related Concept Videos
One-Compartment Model: IV Infusion
The one-compartment model for IV infusion uses mathematical equations to describe the rate of change in drug quantity in the body. At steady-state or infusion equilibrium, the drug input...
IV Infusion to Oral Dosing: Conversion Methods
Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices
Two-Compartment Open Model: IV Infusion
The model illustrates the decrease in plasma drug concentration from the central compartment with a specific equation. It shows that under steady-state conditions, the drug's input rate...
Drug Dosing: Infants and Children
Drug Accumulation During Multiple Dosing: Intermittent IV Infusions

