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Related Experiment Video

Updated: Feb 20, 2026

Author Spotlight: Enhancing Cerebral Ischemia Research with a Simplified Rat Model

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Published on: July 5, 2024

Vertebrobasilar ischemia after neck motion.

G B Frisoni¹, G P Anzola

¹Clinica Neurologica dell'Università di Brescia, Spedali Civili, Italy.

|November 1, 1991

Summary

This summary is machine-generated.

Vertebrobasilar ischemic strokes can occur after chiropractic neck manipulation. Risk factors are difficult to identify, and severe outcomes are common, necessitating caution.

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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

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Published on: August 18, 2015

Area of Science:

Neurology
Vascular Surgery
Chiropractic Medicine

Background:

Cervical spine manipulation and abrupt head movements are potential triggers for vertebrobasilar ischemic strokes.
These strokes affect the brainstem, cerebellum, or occipital lobes, often with severe consequences.

Observation:

A review of 39 cases, including three new ones, highlights the unpredictable nature of these events.
Clinical presentations vary, with Wallenberg's syndrome and other brainstem syndromes being most common.

Findings:

A significant risk of mortality or severe long-term impairment (28%) exists.
Identifying at-risk individuals is challenging, as symptoms can follow uneventful manipulations.
Contraindications include prior transient neurological symptoms, ligament laxity, and specific vertebral artery anatomy.

Implications:

The pathogenetic mechanism involves vertebral artery dissection at the atlantoaxial joint, leading to thrombosis or embolism.
Healthcare providers should exercise extreme caution with cervical manipulation due to the potential for devastating neurological outcomes.