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[Anti-angiogenic therapy in ocular disease--current and future strategies]
H Agostini1, N Feltgen, L Hansen
1Universitäts-Augenklinik Freiburg. hansjuergen.agostini@uniklinik-freiburg.de
Abstract:
Originating from therapeutic concepts in oncology, angioinhibitory strategies have changed the way ophthalmological patients are treated for a variety of diseases like age-related macular degeneration, diabetic retinopathy or retinal vein occlusion. It is likely that these therapeutic options will not be limited to retinal disease, but will also prove useful for corneal disorders associated with lymph- or angiogenesis. This review is intended to provide a concise overview of the current options investigated in clinical trials.
Insights
Angioinhibitory strategies, initially from cancer therapy, are revolutionizing eye disease treatment. These therapies show promise for retinal conditions and may extend to corneal disorders involving new blood vessel growth.
Area of Science:
- Ophthalmology
- Oncology
- Angiogenesis Inhibition
Context:
- Therapeutic concepts from oncology have been adapted for ophthalmology.
- Angioinhibitory strategies are now standard for retinal diseases such as age-related macular degeneration, diabetic retinopathy, and retinal vein occlusion.
Purpose:
- To provide a concise overview of current angioinhibitory options investigated in clinical trials for ophthalmic disorders.
Summary:
- This review focuses on angioinhibitory strategies, highlighting their successful application in retinal diseases.
- It explores the potential of these therapies for corneal disorders characterized by lymph- or angiogenesis.
Impact:
- Angioinhibitory strategies have significantly altered the treatment landscape for major retinal diseases.
- Future applications may expand to include corneal conditions, offering new therapeutic avenues.
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