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Published on: July 3, 2019
[Effects of centipede extract on life span of drosophila]
Xiao-dong Cui1, Chao-ran Wang, Chang-qing Zhang
1School of Chinese Material Medica, Beijing University of Traditional Chinese Medicine, Beijing 100102, China.
Objective:
To evaluate effects of centipede on life span of drosophila and on the appearance of the filial generation.
Methods:
Drosophila melanogaster (male and female) were cultured in tubes with centipede extraction at concentrations of 0, 0.2%, 1%, 2.5%, or 5% until all drosophila died. The appearance of the filial generation were observed.
Results:
The life span, including average, longest and shortest life span was shortened in exposed groups of both sexes and significantly dose-dependent. The appearance of the filial generation showed normal.
Conclusion:
Centipede extracts accelerates the aging of drosophila and shortens their life span. The appearance of the filial generation is not affected. Clinic using centipede for a long period should be carefully.
