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Published on: December 5, 2017
Exploring heterogeneity in meta-analyses: needs, resources and challenges
Hairong Xu1, Robert W Platt, Zhong-Cheng Luo
1Department of Obstetrics and Gynecology, Hôpital Sainte-Justine, Université de Montréal, Montréal, Québec, Canada.
Abstract:
The investigation of heterogeneity remains an essential but difficult issue in the conduct of meta-analysis. We reviewed standard and graphical methods used to explore heterogeneity in meta-analysis and publications from January 2005 to April 2007 regarding meta-analyses that focused on perinatal health topics. We assessed their approaches to the investigation of heterogeneity, including: (1) whether statistical testing for heterogeneity was performed and, if so, which test was used, (2) how a finding of statistically significant heterogeneity was handled, and (3) how the analyses were conducted in the presence of heterogeneity.
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