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Cyclic nausea and vomiting in childhood
David Forbes1, Susan Fairbrother
1School of Paediatrics & Child Health, University of Western Australia. dforbes@meddent.uwa.edu.au
Insights
Cyclic vomiting syndrome (CVS) is a common functional gastrointestinal disorder in children, characterized by severe nausea and vomiting episodes. Early recognition and tailored management are crucial for improving outcomes.
Area of Science:
- Pediatric Gastroenterology
- Functional Gastrointestinal Disorders
Background:
- Cyclic vomiting syndrome (CVS) is an under-recognized functional gastrointestinal disorder in childhood.
- It is relatively common and can be disabling, despite frequent misdiagnosis by healthcare providers.
Purpose of the Study:
- To describe the clinical features of CVS in children.
- To outline the differential diagnosis, treatment strategies, and expected outcomes for pediatric CVS.
Main Methods:
- This article is a descriptive review of Cyclic Vomiting Syndrome.
- Information is synthesized from existing literature on clinical features, diagnosis, and management.
Main Results:
- CVS affects approximately 2% of children, presenting as recurrent, severe vomiting episodes with symptom-free intervals.
- Associated conditions include migraine, genetic factors, autonomic dysregulation, and anxiety. Triggers can be stress, infection, or food.
Conclusions:
- Diagnosis of CVS requires excluding other causes of vomiting.
- Management involves preventing attacks, terminating vomiting, sedation, and preventing complications.
- Children may improve, develop migraines, or experience ongoing symptoms into adulthood.
Background:
Cyclic vomiting syndrome (CVS) is an under-recognised functional gastrointestinal disorder of childhood. Despite failure of recognition by many health practitioners, it is relatively common and frequently disabling.
Objective:
This article describes the clinical features, differential diagnosis, treatment and outcomes of CVS.
Discussion:
Cyclic vomiting syndrome is a functional disorder in childhood with a prevalence of around 2%. It consists of recurrent paroxysms of severe nausea and vomiting separated by symptom free periods. Associations include migraine, genetic factors, autonomic dysregulation, neuromuscular disorders and a tendency to anxiety. Cyclic vomiting syndrome may be triggered by stress and anticipatory anxiety as well as infection, exercise, trauma, menstruation and foods. Diagnosis requires exclusion of other causes of nausea and vomiting. Management focuses on the phases of the illness: prevention of attacks, termination of vomiting, sedation and prevention of complications. Children may outgrow symptoms, develop migraine or continue to have episodes into adulthood.
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