Related Experiment Video
Updated: Jul 7, 2026

Dynamic Proteomic and miRNA Analysis of Polysomes from Isolated Mouse Heart After Langendorff Perfusion
Published on: August 29, 2018
Cardiovascular Initiative of the Human Proteome Organisation, 5th Workshop October 2007, Seoul, Korea
Sarah Warburton1, Melanie Y White, Jennifer E Van Eyk
1Department of Anesthesiology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
Insights
The Cardiovascular Initiative (CVI) of the Human Proteome Organisation (HUPO) held its fifth workshop. This report details the CVI
Area of Science:
- Cardiovascular Science
- Proteomics
- Biomedical Research
Background:
- The Human Proteome Organisation's Cardiovascular Initiative (CVI) convened its fifth workshop in Seoul, Korea, preceding the Sixth Annual HUPO World Congress in October 2007.
- This event aimed to introduce the CVI's history and objectives to a broader scientific audience.
- The workshop served as a platform to disseminate information about ongoing and future collaborative proteomic research in cardiovascular disease.
Framework:
- The CVI operates as a collaborative framework within HUPO, focusing on proteomic research relevant to cardiovascular health and disease.
- It aims to foster international cooperation and standardization in cardiovascular proteomics.
- Key objectives include identifying and validating cardiovascular biomarkers and understanding disease mechanisms at the proteome level.
Implementation:
- The workshop featured lectures by CVI members, highlighting key research areas and progress.
- Discussions focused on the historical development and foundational principles of the CVI.
- Current and prospective collaborative projects were presented to encourage community engagement and participation.
Implications:
- Increased awareness of the CVI's mission and activities within the global scientific community.
- Potential for enhanced collaboration and resource sharing in cardiovascular proteomics research.
- Advancement of proteomic strategies for improved understanding, diagnosis, and treatment of cardiovascular diseases.
Abstract:
The Cardiovascular Initiative (CVI) of the Human Proteome Organisation (HUPO) held its fifth workshop prior to the Sixth Annual HUPO World Congress in Seoul, Korea in October 2007. The objectives of this report are as follows: to trace the (relatively brief) history of the CVI for those who may not be acquainted with it; to highlight lectures given by members of the CVI during this Workshop; and to make the community aware of the aims of this Initiative, including collaborative projects currently under consideration.
Related Concept Videos
Blood Studies for Cardiovascular System I: Cardiac Biomarkers
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
Blood Studies for Cardiovascular System III: Serum Lipid Profile
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Regulation of the Cardiovascular System
The regulation of the cardiovascular system involves the autonomic nervous system (ANS), baroreceptors, and chemoreceptors, ensuring that heart rate and blood pressure are appropriately modulated in response to varying physiological demands.
The ANS comprises two main divisions: the sympathetic and parasympathetic nervous systems. The sympathetic nervous system enhances...
Proteomics
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...
Cardiomyopathy V: Interprofessional Care

