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Updated: Jul 7, 2026

Therapeutic Massage for Psychological Well-being in Geriatric Oncology
Published on: May 22, 2026
Physical activity in patients with advanced-stage cancer actively receiving chemotherapy
Matthew M Clark1, Kristin S Vickers, Julie C Hathaway
1Department of Psychiatry and Psychology, Cancer Treatment Unit, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. clark.matthew@mayo.edu
Abstract:
Exercise has mental and physical health benefits for patients with advanced stage cancer who actively receive chemotherapy, yet little is known about patients'levels of interest in becoming more active or their confidence in increasing their activity level. A convenience sample of 128 patients with advanced-stage cancer who were receiving chemotherapy completed self-report measures assessing physical activity level, mood, and quality-of-life variables. Qualitative data on patient-perceived benefits of, and barriers to, physical activity also were collected, coded by independent raters, and organized by predominant themes. Fatigue was the most frequently listed barrier to physical activity; improved physical strength and health were the most commonly listed benefits. Participants identified benefits related to both general health and cancer-symptom management that were related to exercise. Over 50% of participants reported that they were seriously planning to increase or maintain their physical activity level, and 47% reported having interest in receiving an intervention to become more active. Future research will investigate how these findings may be incorporated into physical activity interventions for advanced-stage oncology patients receiving medical treatment.
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