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Use of Label-free Optical Biosensors to Detect Modulation of Potassium Channels by G-protein Coupled Receptors
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Use of Label-free Optical Biosensors to Detect Modulation of Potassium Channels by G-protein Coupled Receptors

Published on: February 10, 2014

Label-free optical biosensor for ligand-directed functional selectivity acting on beta(2) adrenoceptor in living

Ye Fang1, Ann M Ferrie

  • 1Biochemical Technologies, Science and Technology Division, Corning Incorporated, Sullivan Park, Corning, NY 14831, USA. fangy2@corning.com

FEBS Letters
|February 5, 2008
PubMed

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Ligand Binding Sites02:40

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Protein-ligand interactions are quite specific; even though numerous potential ligands surround a cellular protein at any given time, only a particular ligand can bind to that protein. Moreover, a ligand binds only to a dedicated area on the surface of the protein, known as the...