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Sildenafil for pulmonary hypertension: dose-dependent improvement in exercise performance

Riina Marjaana Spring1, Silvia Ulrich, Lars C Huber

  • 1Department of Internal Medicine, University Hospital, Raemistrasse 100, CH-8091 Zurich, Switzerland.

Pulmonary Pharmacology & Therapeutics
|February 6, 2008
PubMed
Summary

Sildenafil at 50mg three times daily significantly improved 6-minute walking distance (6-MWD) in patients. Lower doses of 12.5mg and 25mg showed no significant changes in 6-MWD, indicating a dose-response relationship.

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