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Dietary exclusions for established atopic eczema
F Bath-Hextall1, F M Delamere, H C Williams
1School of Nursing, University of Nottingham, Faculty of Medicine and Health Science, Room D83, Medical School, Queens Medical Centre, Nottingham, UK, NG7 2UH. fiona.bath-hextall@nottingham.ac.uk
The Cochrane Database of Systematic Reviews
|February 7, 2008
Summary
Dietary exclusion diets show limited benefit for atopic eczema (AE) in most individuals. An egg-free diet may help infants with confirmed egg allergy and specific IgE levels.
Area of Science:
- Dermatology
- Allergology
- Clinical Nutrition
Background:
- Atopic eczema (AE) is a chronic inflammatory skin condition causing itchy rashes.
- Dietary interventions are explored for managing AE symptoms.
Purpose of the Study:
- To evaluate the effectiveness of various dietary exclusion strategies in treating established atopic eczema.
Main Methods:
- A comprehensive literature search was conducted across multiple databases up to March 2006.
- Included randomized controlled trials (RCTs) involving individuals diagnosed with atopic eczema.
- Study selection and quality assessment were performed by two independent reviewers.
Main Results:
- Nine RCTs with 421 participants were analyzed, focusing on egg/milk exclusion, few-food diets, and elemental diets.
- No significant benefit was observed for egg and milk exclusion, elemental, or few-food diets in unselected AE patients.
- A potential benefit of an egg-free diet was noted in infants with suspected egg allergy and positive specific IgE, though study limitations necessitate caution.
Conclusions:
- Limited evidence supports general dietary exclusion diets for atopic eczema.
- An egg-free diet may benefit infants with confirmed egg allergy.
- Future research should focus on larger, well-designed trials in participants with proven food allergies.
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