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[Diabetes mellitus in children in Lomé (Togo)]
Adama Dodji Gbadoé1, Raymond Barruet, Koko Lawson-Evi
1Service de pédiatrie, CHU-Tokoin Lomé, Togo.
Insights
The emergence of type 2 diabetes mellitus (T2DM) in children in Lomé, Togo, is characterized by obesity and a family history of diabetes. Early diagnosis and management, including lifestyle changes, are crucial for successful treatment outcomes.
Area of Science:
- Pediatric Endocrinology
- Metabolic Disorders
- Public Health
Context:
- Diabetes mellitus in children presents unique challenges in resource-limited settings.
- Understanding the epidemiological shifts in diabetes types is critical for public health.
- Lomé, Togo, serves as a specific geographical focus for this pediatric diabetes study.
Purpose:
- To describe the clinical characteristics and outcomes of children diagnosed with diabetes mellitus in Lomé, Togo.
- To differentiate between type 1 diabetes mellitus (T1DM), type 2 diabetes mellitus (T2DM), and corticosteroid-induced diabetes in pediatric patients.
- To identify key risk factors associated with T2DM in the pediatric population.
Summary:
- The study analyzed 18 children admitted for diabetes between 1997 and 2004.
- Diagnoses included 12 T1DM, 5 T2DM, and 1 corticosteroid-induced diabetes.
- T2DM risk factors identified were obesity and familial history; T1DM also showed familial links.
- Clinical presentations often included polyuria, polydipsia, and ketonuria.
- T2DM patients were obese with unhealthy lifestyle factors; T1DM patients required insulin, while T2DM patients were managed with insulin, exercise, and diet.
Impact:
- Highlights the increasing prevalence of T2DM in children in Togo, shifting the clinical landscape.
- Emphasizes the role of obesity and genetics in pediatric T2DM.
- Informs public health strategies and clinical management guidelines for childhood diabetes in similar regions.
- Demonstrates successful treatment modalities for both T1DM and T2DM in pediatric populations.
Aim:
Describe clinical aspects and outcome of children with diabetes mellitus in Lomé (Togo).
Methods:
This work concern eighteen children consecutively admitted between 1997 and 2004 for diabetes mellitus. Diagnosis of type 2 diabetes mellitus (T2DM) were done on the presentation of at least one of T2DM risk factors: obesity, familial history of T2DM, acanthosis nigricans, polycystic ovary syndrome, dislipidemia, high blood pressure.
Results:
Twelve children presented type 1 diabetes mellitus (T1DM), 5 T2DM and one, corticosteroids induced diabetes. At least one of the first degree parent suffered from diabetes in 4 of the 5 children with T2DM and 4 of the 12 patients with T1DM. Most patients (with T1DM or T2DM) presented polyuria, polydypsia and ketonuria at admission. All patients with T2DM were obese and had lifestyles characterised by high fat intake, sedentary attitudes, and physical inactivity. The corticosteroid induced diabetes cessed when corticosteroid stopped. The other patients were successfully treated with insulin (T1DM) or insulin then exercises and diets (T2DM).
Conclusion:
Clinical presentation of diabetes mellitus is now characterised in Togo by the emergence of T2DM which principal risks factors are obesity and familial history of T2DM.
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