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Updated: Jul 7, 2026

Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide
Published on: January 15, 2017
Specialized centers and systems for heart attack care
1Christ Hospital Heart and Vascular Center, The Lindner Research Center, and Ohio State University, Cincinnati, OH 45219, USA. lindner@fuse.net
Insights
Primary percutaneous coronary intervention significantly improves outcomes for ST-segment elevation myocardial infarction (STEMI) compared to fibrinolysis. Developing regional STEMI networks is crucial for timely treatment delivery.
Area of Science:
- Cardiology
- Public Health Systems
- Emergency Medicine
Background:
- Primary percutaneous coronary intervention (PCI) offers superior outcomes for ST-segment elevation myocardial infarction (STEMI) compared to fibrinolytic therapy.
- Timely and expert delivery of primary PCI to all STEMI patients remains a significant healthcare challenge.
Purpose of the Study:
- To review the rationale and inherent challenges in developing regional systems of care for STEMI patients.
- To explore the concept of regional STEMI networks for improved treatment accessibility.
Main Methods:
- Review of evidence from randomized controlled trials and clinical registries.
- Analysis of existing models for trauma and stroke care networks.
- Discussion of the logistical and systemic issues in implementing regional STEMI care.
Main Results:
- Primary PCI is the preferred reperfusion strategy for STEMI.
- Current healthcare systems face challenges in providing widespread access to primary PCI.
- Regionalization of care, through centers of excellence and networks, is proposed as a solution.
Conclusions:
- Establishing regional STEMI networks is essential to overcome barriers to timely primary PCI.
- System-level improvements are necessary to ensure equitable and effective STEMI care.
- Models similar to trauma and stroke networks can be adapted for STEMI management.
Abstract:
Evidence from randomized controlled clinical trials and registries suggest that primary percutaneous coronary intervention provides superior clinical outcomes when compared with fibrinolytic therapy for the treatment of ST segment elevation myocardial infarction (STEMI). However, the delivery of expert and timely primary percutaneous coronary intervention to the majority of patients with STEMI is extremely challenging. This objective has fueled the concept of regional centers of excellence for the care of patients with STEMI as well as regional STEMI networks similar to those currently available for trauma or stroke victims. This article reviews the rationale behind, as well as the issues inherent to, the development of systems of care for STEMI patients.
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