Related Experiment Video
Updated: Jul 7, 2026

12:08
Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
Improving glycemic control in medical inpatients: a pilot study
Jennifer M Trujillo1, Emily E Barsky, Bonnie C Greenwood
1Northeastern University School of Pharmacy, Boston, MA 02115, USA. j.trujillo@neu.edu
Journal of Hospital Medicine
|February 8, 2008
Summary
Implementing a new inpatient insulin protocol showed fair adherence, with barriers like fear of hypoglycemia and clinical inertia hindering improved glycemic control. Further quality improvement efforts are needed.
Area of Science:
- Internal Medicine
- Endocrinology
- Quality Improvement
Background:
- Inpatient hyperglycemia is linked to adverse patient outcomes.
- Current guidelines suggest maintaining blood glucose below 180 mg/dL in non-ICU settings.
Purpose of the Study:
- To implement a subcutaneous insulin protocol in a general medicine service.
- To identify barriers to protocol implementation.
- To assess the protocol's impact on glycemic control.
Main Methods:
- Prospective quality-improvement pilot study involving 89 patients with type 2 diabetes or hyperglycemia.
- Evaluated resident acceptance, insulin ordering practices, and mean hyperglycemia rate.
- Compared results with a prior observational study.
Main Results:
- Resident agreement to use the protocol was 56%.
- Barriers included disease severity, oral medication titration, and hypoglycemia concerns.
- Hyperglycemia rates did not significantly differ between the pilot and baseline groups.
Conclusions:
- Adherence to the inpatient subcutaneous insulin protocol was moderate.
- Key barriers identified were fear of hypoglycemia, delayed basal insulin initiation, and clinical inertia.
- Targeting these barriers is crucial for enhancing inpatient glycemic management.
Related Concept Videos
Dipeptidyl Peptidase 4 Inhibitors
Dipeptidyl peptidase 4 (DPP-4) is a serine protease widely distributed in the body. It's involved in the inactivation of GLP-1 and GIP hormones, which are crucial for insulin regulation. DPP-4 inhibitors, such as sitagliptin (Januvia), saxagliptin (Onglyza), linagliptin (Tradjenta), alogliptin (Nesina), and vildagliptin (Galvus), help increase the proportion of active GLP-1, enhancing insulin secretion. These inhibitors work by competitively binding to DPP-4. This binding causes a significant...
Diabetes: Management and Pharmacotherapy
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Hypoglycemia and Glucagon
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
SBAR II: Application of SBAR
SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...