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Updated: Jul 7, 2026
High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC
Published on: February 2, 2024
[Studies on chemical constituents in the buds of Tussilago farfara]
Yu-feng Liu1, Xiu-wei Yang, Bin Wu
1Department of Natural Medicines, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100083, China.
Objective:
To study the chemical constituents in the buds of Tussilago farfara.
Method:
The chemical constituents were isolated by various column chromatographic methods and structurally elucidated by NMR and MS evidences.
Result:
Eleven compounds were obtained and identified as methyl 3, 4-O-dicaffeoylquinate (1), methyl 3, 5-O-dicaffeoylquinate (2), methyl 4, 5-O-dicaffeoylquinate (3), 3, 5-O-dicaffeoylquinic acid (4), methyl 3-O-caffeoylquinate (5), 3-O-caffeoylquinic acid (6), hyperoside (7), rutin (8), kaempferol 3-O-beta-D-glucopyranoside (9), quercetin (10), and kaempferol (11).
Conclusion:
Compounds 2-5 were isolated from the genus for the first time.