Related Experiment Video
Updated: Jul 7, 2026

Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits
Published on: January 8, 2020
Lacrimal caruncle nevus associated with Rubinstein-Taybi syndrome
Arkadiusz Pogrzebielski1, Anna Piwowarczyk, Joanna Kohylarz
1Department of Ophthalmology and Ocular Oncology, Jagiellonian University, Krakow, Poland.
Abstract:
We present a 28-year-old man with diagnosed Rubinstein-Taybi syndrome (RSTS), known as "Broad thumb-Hallux syndrome" with co-existing lacrimal caruncle tumor. Because of the documented enlargement of the lacrimal caruncle mass and known increased risk to develop malignancies in RSTS patients we decided to perform excisional biopsy, which revealed caruncle nevus. To our knowledge this is the first description of such an association.
Related Concept Videos
The Retinoblastoma Gene
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
Accessory Structures of the Eye

