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Semi-quantitative Assessment Using [18F]FDG Tracer in Patients with Severe Brain Injury
Published on: November 9, 2018
[Non-paraneoplastic limbic encephalitis revealed by anterograde amnesia]
Pierre Olivier Lang1, François Sellal
1Service de médecine interne et réadaptation, Département de réhabilitation et gériatrie, Hôpitaux Universitaires de Genève, Hôpital des Trois-Chêne, 3 chemin du Pont-Bochet, CH-1226 Thônex-Genève, Suisse. Pierre.O.Lang@hcuge.ch
Presse Medicale (Paris, France : 1983)
|February 12, 2008
Summary
Limbic encephalitis, a paraneoplastic syndrome, can present with amnesia. This case highlights non-neoplastic causes and characteristic MRI findings of hippocampal lesions.
Area of Science:
- Neurology
- Radiology
- Oncology
Background:
- Limbic encephalitis is a neurological syndrome often linked to an undiagnosed cancer.
- It typically presents with progressive neurological symptoms over weeks.
Observation:
- A 56-year-old man experienced anterograde amnesia, indicative of limbic encephalitis.
- Magnetic resonance imaging revealed bilateral hippocampal lesions with specific signal characteristics.
Findings:
- The case suggests a non-neoplastic etiology for limbic encephalitis based on clinical, laboratory, and imaging data.
- Five-year follow-up confirmed the absence of malignancy.
Implications:
- This case underscores the importance of considering non-paraneoplastic causes of limbic encephalitis.
- It offers insights into comparing radiologic, imaging, and neurologic findings in bilateral hippocampal lesions.
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