Related Experiment Video
Updated: Jul 7, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
Lyme disease with lymphocytic meningitis, trigeminal palsy and silent thalamic lesion
Joachim Köchling1, Hans J Freitag, Thomas Bollinger
1Klinik für Kinder- und Jugendmedizin, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany. koechling@paedia.ukl.mu-luebeck.de
Abstract:
We describe a follow-up in a 15-year-old boy with neuroborreliosis diagnosed by clinical symptoms, CSF and serum analysis. MRI revealed a thalamic lesion and an enhancement of the right trigeminal nerve clinically associated with mild hypasthesia in the right maxillary region. Both, clinical symptoms and radiological findings disappeared within 2 months after treatment. Borrelia burgdorferi specific IgM and IgG in CSF and IgG in serum became negative between 6 and 12 months after diagnosis. We show that neuroborreliosis at an early stage may present only with moderate neurological deficits and that at this stage MRI reveals distinct cerebral lesions which might even precede clinical manifestation. Thus, early diagnosis and treatment of neuroborreliosis may prevent persistent neurologic lesions.
Related Concept Videos
Encephalitis l: Introduction
Bacterial Meningitis I: Introduction
Viral Meningitis
Encephalitis ll: Pathophysiology
Multiple Sclerosis l: Introduction
Bacterial Meningitis
