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Updated: Jul 7, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
[Microbiological and clinical diagnosis of acute endophthalmitis]
C Chiquet1, Y Benito, J Croize
1Service d'Ophtalmologie, Hôpital Michallon, Université J. Fourier, CHU de Grenoble, Grenoble, France. cchiquet@chu-grenoble.fr
Abstract:
The microbiological study identifies the bacterial spectrum after surgery, in acute, delayed-onset, or chronic endophthalmitis. DNA amplification of eubacterium-specific sequences in DNA extracted from ocular samples is a new tool for the etiological diagnosis of endophthalmitis. The most successful way to identify bacteria in endophthalmitis is the association of conventional cultures and panbacterial PCR on vitreous samples. Both techniques are complementary. The efficacy of these new molecular techniques should modify our future therapeutic strategies.
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