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Exacerbation of granular corneal dystrophy type II (Avellino corneal dystrophy) after LASEK
Jae Hwan Lee1, R Doyle Stulting, Dong Ho Lee
1Department of Ophthalmology, Corneal Dystrophy Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Purpose:
To report cases of granular corneal dystrophy type II (Avellino corneal dystrophy) that were exacerbated by uncomplicated laser epithelial keratomileusis (LASEK) for myopia.
Methods:
Eight patients (15 eyes) with granular corneal dystrophy type II who underwent LASEK were examined by DNA sequencing, slit-lamp microscopy, and confocal microscopy.
Results:
The number and density of the opacities increased after LASEK. Best spectacle-corrected visual acuity decreased after LASEK as the density of the opacities increased. In three patients, mitomycin C was used intraoperatively, but corneal deposits also worsened in these patients.
Conclusions:
LASEK is contraindicated in patients with granular corneal dystrophy type II because vision may be reduced from an increase in the density of corneal opacities postoperatively.
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