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Synovial fluid immunocytology in the diagnosis of leukemic synovitis
A G Fam1, C Voorneveld, J B Robinson
1Department of Medicine, Sunnybrook Health Science Centre, University of Toronto, ON, Canada.
The Journal of Rheumatology
|February 1, 1991
Abstract:
We describe a patient with leukemic synovitis complicating acute lymphoplastic leukemia. Leukemic cells were identified in the synovial fluid by an indirect immunofluorescent technique using monoclonal antibodies against early B cell antigens. Since focal leukemic lesions may be missed in synovial biopsy specimens, immunocytological analysis of joint fluids may facilitate early diagnosis of leukemic arthritis.