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Need for cognitive rehabilitation for children with sickle cell disease and strokes

Allison A King1, Michael R DeBaun, Desiree A White

  • 1Washington University School of Medicine, Program in Occupational Therapy, Campus Box 8505, 4444 Forest Park Ave., St. Louis, MO 63108, USA. king_a@kids.wustl.edu

Expert Review of Neurotherapeutics
|February 15, 2008
PubMed

Insights

Children with sickle cell disease (SCD) and stroke face cognitive challenges. A pilot cognitive rehabilitation program showed feasibility but requires further research to confirm its effectiveness in improving memory and educational outcomes.

Area of Science:

  • Pediatric Neurology
  • Hematology
  • Neurorehabilitation

Background:

  • Stroke is a major cause of illness in children with sickle cell disease (SCD).
  • About 30% of children with sickle cell anemia experience overt stroke or silent infarcts, leading to brain injury.
  • These neurological events are linked to cognitive deficits and lower educational achievement.

Purpose of the Study:

  • To pilot a cognitive rehabilitation program for children with SCD and stroke.
  • To assess the feasibility of improving memory and educational attainment in this population.

Main Methods:

  • A cognitive rehabilitation program was implemented.
  • Feasibility and preliminary outcomes related to memory and education were evaluated.

Main Results:

  • The cognitive rehabilitation intervention was found to be feasible for children with SCD and stroke.
  • Further research is necessary to establish the program's efficacy.

Conclusions:

  • Cognitive rehabilitation holds promise for children with SCD and stroke.
  • Collaboration between health and educational systems is crucial for improving cognitive and educational outcomes.
  • Ongoing studies aim to enhance cognitive function in these children.

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