Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Compact Integrated Optical Immunosensor using Replicated Chirped Grating Coupler Sensor Chips.

J Dübendorfer, R E Kunz

    Applied Optics
    |February 15, 2008
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Sensing and reference pads for integrated optical immunosensors.

    Journal of biomedical optics·2012
    Same author

    Refractive and diffractive properties of planar micro-optical elements.

    Applied optics·2010
    Same author

    Arrays of anamorphic phase-matched Fresnel elements for diode-to-fiber coupling.

    Applied optics·2010
    Same author

    Miniature integrated-optical wavelength analyzer chip.

    Optics letters·2009
    Same author

    Analysis and optimization of fabrication of continuous-relief diffractive optical elements.

    Applied optics·2008
    Same author

    Wavelength-interrogated optical sensor for biochemical applications.

    Optics letters·2007
    Same journal

    Multifunctional reconfigurable terahertz metasurface based on vanadium dioxide phase transition: achieving broadband absorption and efficient polarization conversion.

    Applied optics·2026
    Same journal

    High-Q-factor electromagnetically induced transparency utilizing quasi-bound states in the continuum in an all-dielectric terahertz metasurface.

    Applied optics·2026
    Same journal

    Automated stitching interferometry for high-precision metrology of X-ray mirrors.

    Applied optics·2026
    Same journal

    Experimental demonstration of an approach to designing a metal-dielectric DBR resonant cavity structure.

    Applied optics·2026
    Same journal

    High-precision wavefront reconstruction from a single-shot interferogram using a physics-driven hybrid feature calibration network.

    Applied optics·2026
    Same journal

    Ultra-high-Q Fano resonance based on coupled topological corner states in Kagome photonic crystals.

    Applied optics·2026
    See all related articles

    This study introduces a new compact optical sensor for detecting molecule adsorption. The integrated sensor achieved high sensitivity in an immunosensor experiment, demonstrating its practical application.

    Area of Science:

    • Integrated optics
    • Biosensing technology
    • Nanomaterial applications

    Background:

    • Optical sensors offer high sensitivity for detecting molecular interactions.
    • Integrated optical modules enable miniaturization and enhanced functionality.
    • Chirped grating couplers are effective for signal transduction in optical sensing.

    Purpose of the Study:

    • To describe a novel compact multichannel integrated optical sensor module.
    • To demonstrate the sensor's performance in measuring mass adsorption of analyte molecules.
    • To validate the use of chirped grating couplers for signal transduction.

    Main Methods:

    • Fabrication of a compact multichannel integrated optical sensor module.
    • Utilizing chirped grating couplers for signal transduction.

    Related Experiment Videos

  • Performing refractometry in an immunosensor experiment with TiO(2) waveguide sensor chips.
  • Detecting the binding of rabbit immunoglobulin to immobilized protein A.

    • Main Results:

    • The optical sensor module successfully measured mass adsorption of analyte molecules.
    • A resolution of approximately 3 pg/mm(2) surface mass coverage was achieved.
    • The sensor demonstrated high sensitivity in detecting specific molecular binding events.

    Conclusions:

    • The novel compact multichannel integrated optical sensor module is effective for biosensing applications.
    • Chirped grating couplers provide a simple yet highly functional approach for sensor module construction.
    • The sensor technology shows promise for sensitive and specific detection of biomolecular interactions.