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Updated: Jul 7, 2026

Multifocal Electroretinograms

Multifocal Electroretinograms

Published on: December 4, 2011

Multifocal fibrosclerosis: a new case report.

A J Sommerfield¹, K A Lockman, A J Bathgate

¹Department of Diabetes and Endocrinology, Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh, UK.

Annals of Clinical Biochemistry

|February 16, 2008

Summary

This summary is machine-generated.

This case study details a patient with cranial diabetes insipidus who developed pituitary failure, mesenteric fibrosis, and primary sclerosing cholangitis. These conditions may stem from a rare unifying diagnosis of progressive multifocal fibrosclerosis.

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Area of Science:

Endocrinology
Gastroenterology
Pathology

Background:

Cranial diabetes insipidus and anterior pituitary failure are distinct endocrine disorders.
Mesenteric fibrosis and primary sclerosing cholangitis are gastrointestinal and hepatobiliary conditions, respectively.

Observation:

A single patient presented with isolated cranial diabetes insipidus, later developing progressive anterior pituitary failure.
The same patient exhibited evidence of mesenteric fibrosis and primary sclerosing cholangitis.

Findings:

The patient's pituitary disease is hypothesized to be caused by progressive fibrosis.
The disparate conditions observed in the patient suggest a potential link.

Implications:

Progressive multifocal fibrosclerosis, a rare fibro-inflammatory process, may unify these seemingly unrelated pathologies.
This case highlights the potential for fibrosclerosis to affect multiple organ systems, including the pituitary and gastrointestinal tract.