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A Facile Protocol to Generate Site-Specifically Acetylated Proteins in Escherichia Coli
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Published on: December 9, 2017

Genetically encoding N(epsilon)-acetyllysine in recombinant proteins.

Heinz Neumann1, Sew Y Peak-Chew, Jason W Chin

  • 1Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 0QH England, UK.

Nature Chemical Biology
|February 19, 2008
PubMed
Summary

Scientists developed a new method to insert N(epsilon)-acetyllysine into proteins at specific sites. This breakthrough in protein synthesis will help researchers understand the role of this important post-translational modification.

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