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New viral vaccines for dermatologic disease
Christine Orlova Urman1, Alice B Gottlieb
1Tufts University School of Medicine, Boston, Massachusetts, USA. Christine.Orlova@tufts.edu
Journal of the American Academy of Dermatology
|February 19, 2008
Summary
Two new vaccines, the human papillomavirus (HPV) vaccine and the herpes zoster (HZ) vaccine, are now available to prevent cervical cancer, genital warts, and shingles. These vaccines will significantly impact dermatologic practice and reduce disease-related healthcare burdens.
Area of Science:
- Virology
- Immunology
- Dermatology
Background:
- Human papillomavirus (HPV) and varicella-zoster virus (VZV) cause significant anogenital diseases and shingles, respectively.
- Recent FDA approvals introduce new vaccines targeting these viral infections.
Purpose of the Study:
- To review the pathophysiology and epidemiology of HPV-related diseases and herpes zoster.
- To summarize clinical trial data on the efficacy and safety of new HPV and HZ vaccines.
Main Methods:
- Review of scientific literature on HPV and VZV infections.
- Analysis of clinical trial results for HPV and HZ vaccines.
Main Results:
- New HPV vaccine reduces infection with common types causing cervical cancer and genital warts.
- New HZ vaccine prevents shingles and its complications.
Conclusions:
- The introduction of HPV and HZ vaccines is expected to decrease the global healthcare burden of these viral diseases.
- These vaccines represent a significant advancement in preventing anogenital cancers and shingles.
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