Related Experiment Video
Updated: Jul 7, 2026
03:53
Regenerative Peripheral Nerve Interface: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain
Published on: March 15, 2024
A randomized, controlled trial of the reciprocating procedure device for local anesthesia
Sharon E Nunez1, Edward J Bedrick, Sharon C Kettwich
1Department of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA.
The Journal of Emergency Medicine
|February 19, 2008
Summary
The new reciprocating procedure device (RPD) significantly outperforms the conventional syringe in local anesthesia delivery. It reduces administration time, pain, and procedure discomfort while improving physician satisfaction.
Area of Science:
- Anesthesiology
- Dental Procedures
- Medical Device Technology
Background:
- Local anesthesia administration is crucial for pain management during various medical and dental procedures.
- Conventional syringe methods can be associated with patient discomfort and prolonged administration times.
- Novel devices aim to improve the efficiency and patient experience of local anesthesia delivery.
Purpose of the Study:
- To evaluate the efficacy and patient experience of a new reciprocating procedure device (RPD) compared to the conventional syringe for local lidocaine anesthesia administration.
- To determine if the RPD offers improvements in administration time, pain perception, and operator satisfaction.
Main Methods:
- A randomized study involving 209 local lidocaine anesthesia procedures.
- Procedures were allocated to either the reciprocating procedure device (RPD) or the conventional syringe.
- Key outcome measures included administration time, anesthesia pain, procedure pain, and operator satisfaction.
Main Results:
- The RPD significantly reduced anesthesia administration time by 49% (p < 0.001).
- Patient-reported pain was reduced by 27% for anesthesia and 74% for the procedure (p < 0.001).
- Physician satisfaction with the device improved by 63% (p < 0.001).
Conclusions:
- The reciprocating procedure device (RPD) is superior to the conventional syringe for local lidocaine anesthesia.
- The RPD offers significant benefits including reduced administration time and patient/procedure pain.
- The RPD enhances operator satisfaction, indicating a favorable clinical profile for local anesthesia delivery.
Related Concept Videos
01:16Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
One of the advantages of...
01:30Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia
Depending on the target organ, local anesthetics (LAs) can be administered via various routes. In surface anesthesia, LAs are applied directly to the surface of the skin or mucous membranes. It is widely used for topical skin numbing before venipuncture or minor surgical procedures. Commonly used surface local anesthetics are lidocaine or benzocaine sprays or creams. Surface anesthesia occurs within 5 minutes and lasts for about 60 minutes. One of the main disadvantages of topical anesthesia is...
01:13Local Anesthetics: Pharmacokinetics
The potency and duration of action of local anesthetics (LAs) are determined by their pharmacokinetics. Pharmacokinetics describes how LAs are absorbed, distributed, metabolized, and eliminated from the body. When administered to the vascular tissues, LAs are quickly absorbed and enter the systemic circulation, reducing their localized effects. Adding vasoconstrictors such as epinephrine to LAs reduces their absorption into the systemic circulation, making them clinically effective. The...
01:29Local Anesthetics: Clinical Application as Epidural Anesthesia
Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...