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Anxiety: Overview

Anxiety: Overview

Anxiety is a common mental disorder featuring excessive worry, fear, and apprehension, significantly affecting daily life. People with anxiety disorders experience persistent and intense anxiety, interrupting their everyday functioning.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.

Social Anxiety Disorder

Social Anxiety Disorder

Social anxiety disorder, also known as social phobia, is characterized by an intense fear of social situations where one might face humiliation, rejection, embarrassment, or negative evaluation. This disorder leads individuals to avoid activities like casual conversations, public speaking, or seemingly simple tasks such as eating, signing documents, or swimming, in public settings. Its impact extends beyond discomfort, often significantly interfering with daily functioning and quality of life.

Anxiolytic Drugs: Overview

Anxiolytic Drugs: Overview

Anxiolytic drugs are vital in managing anxiety disorders by effectively alleviating symptoms such as excessive fear, tachycardia, and tremors. There are several classes of anxiolytic medications, each with unique mechanisms of action and potential side effects.
Primary Types of Anxiolytic Drugs
1. Benzodiazepines:
Benzodiazepines bind to the GABA-A receptor in the brain, enhancing GABA's interaction. This action reduces neurotransmission, effectively blocking anxiety-associated limbic circuitry.

Anxiolytic Drugs: Benzodiazepines and Buspirone

Anxiolytic Drugs: Benzodiazepines and Buspirone

Benzodiazepines are a class of anxiolytic drugs known for their rapid efficacy and high therapeutic-to-lethal dose ratio, but with a potential risk of drug dependence. These drugs are lipophilic, allowing for rapid absorption after oral administration, eventually reaching the central nervous system (CNS). Once in the CNS, benzodiazepines bind to the allosteric site of the GABAA receptor. This binding enhances the inhibitory effects of the neurotransmitter GABA. By doing so, they prevent...

Panic Disorder

Panic Disorder

Panic disorder is an anxiety disorder characterized by recurrent and sudden minutes-long episodes of intense fear, known as panic attacks. These attacks may feel like heart attacks and often happen without warning or a specific cause. They can include symptoms such as rapid heart rate, shortness of breath, chest pain, trembling, sweating, dizziness, and a sense of helplessness. During a panic attack, individuals may feel as though they are experiencing a heart attack or are in a...

Diagnostic and Statistical Manual of Mental Disorders (DSM)

Diagnostic and Statistical Manual of Mental Disorders (DSM)

The Diagnostic and Statistical Manual of Mental Disorders (DSM) serves as the primary classification system for mental health disorders, providing standardized diagnostic criteria for clinicians and researchers. First published by the American Psychiatric Association (APA) in 1952, the DSM has undergone several revisions to reflect evolving psychiatric understanding. The fifth edition, DSM-5, released in 2013, introduced key updates that expanded diagnostic categories and modified diagnostic...

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Related Experiment Video

Updated: Jul 7, 2026

Social Isolation Model: A Noninvasive Rodent Model of Stress and Anxiety

Social Isolation Model: A Noninvasive Rodent Model of Stress and Anxiety

Published on: November 11, 2022

Anxiety disorders and suicidal behaviour: an update.

Jacinta Hawgood¹, Diego De Leo

¹Australian Institute for Suicide Research & Prevention, Griffith University, World Collaborating Centre for Suicide Research and Training, Brisbane, Australia.

Current Opinion in Psychiatry

|February 19, 2008

Summary

Anxiety disorders, including generalized anxiety disorder and panic disorder, are increasingly linked to suicidal behavior. Clinicians should assess anxiety, especially when comorbid with other mental health conditions, to prevent suicide.

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A New Method for Inducing a Depression-Like Behavior in Rats

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

Area of Science:

Psychiatry
Clinical Psychology
Epidemiology

Background:

Anxiety disorders have historically been overlooked as independent risk factors for suicidal behavior.
Clinical assessments and suicide screening tools have not consistently emphasized anxiety disorder evaluation.

Purpose of the Study:

To review literature from January 2006 to May 2007 on the relationship between anxiety and suicidal behavior.
To critically analyze methodological issues and identify future research directions.

Main Methods:

Literature review of studies published between January 2006 and May 2007.
Synthesis of findings on anxiety disorders and suicidality.
Critical evaluation of methodological limitations.

Main Results:

Evidence suggests specific anxiety disorders (e.g., generalized anxiety disorder, panic disorder, obsessive-compulsive disorder) are independently associated with suicidality.
This association is particularly pronounced when anxiety disorders are comorbid with bipolar disorder, depression, schizophrenia, or post-traumatic stress disorder.
Findings apply to both child/adolescent and adult populations.

Conclusions:

Despite methodological limitations, clinicians should specifically evaluate the impact of anxiety disorders on suicidal behavior, especially in comorbid cases.
Further research is needed on the treatment of anxiety disorders for suicide prevention.