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Giant papillary conjunctivitis.

Peter C Donshik1, William H Ehlers, Mark Ballow

  • 1University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030, USA. pdonshik@drdonshik.com

Immunology and Allergy Clinics of North America
|February 20, 2008
PubMed
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Giant papillary conjunctivitis (GPC) causes discomfort and vision issues for contact lens wearers. This review covers GPC symptoms, causes, and effective treatments allowing continued contact lens use.

Area of Science:

  • Ophthalmology
  • Ocular surface disease

Background:

  • Giant papillary conjunctivitis (GPC) is a common complication of contact lens wear.
  • Symptoms include itching, redness, and excessive mucus, leading to poor lens tolerance.

Purpose of the Study:

  • To review the clinical presentation of GPC.
  • To discuss the epidemiology, histology, and pathophysiology of GPC.
  • To outline treatment strategies for GPC patients.

Main Methods:

  • Literature review of clinical signs and symptoms.
  • In-depth review of epidemiology, histology, and pathophysiology.
  • Discussion of various treatment modalities.

Main Results:

  • GPC presents with specific ocular symptoms and signs in contact lens wearers.

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  • Understanding the underlying mechanisms is crucial for management.
  • Multiple treatment options exist to manage GPC.

    • Conclusions:

    • Effective management strategies allow many patients with GPC to continue wearing contact lenses.
    • Further research into preventative measures and novel treatments is warranted.