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A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration
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A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration

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Kentucky rural stimulant use: a comparison of methamphetamine and other stimulant users

William W Stoops1, Michele Staton Tindall, Jennifer R Havens

  • 1University of Kentucky Medical Center, Department of Behavioral Science, COMOB, Lexington, KY 40536-0086, USA. wwstoo0@uky.edu

Journal of Psychoactive Drugs
|February 21, 2008
PubMed

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CNS stimulants, such as cocaine, amphetamines, and cannabinoids, have varying structures and mechanisms of action that lead to different therapeutic effects and side effects. Cocaine, with its molecular formula C17H21NO4, is a tropane alkaloid and a tertiary amino compound. It has two chemical forms: the hydrochloride salt and the "freebase." The former is in powder form, while the latter involves removing the hydrochloride salt to create a form that can be smoked. Cocaine exerts its effects by...
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Hallucinogens, also known as psychedelic drugs, are a class of substances known for their ability to alter perception, cognition, and emotions. Despite their profound effects on the mind, these drugs are non-addictive, setting them apart from many other abused substances. The mechanism of action of these drugs lies in their impact on the 5-HT2A receptor in the brain. Upon activation, this receptor couples to Gq-type G proteins, triggering a cascade that releases intracellular calcium. This...
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Adrenergic Agonists: Mixed-Action Agents

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Adrenergic Agonists: Indirect-Acting Agents

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