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Updated: Jul 7, 2026

Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea
Published on: November 9, 2016
Botulinum toxin A therapy for medial rectus injury during endoscopic sinus surgery
Jenny E Hong1, Andrew N Goldberg, Kimberly P Cockerham
1Department of Ophthalmology, University of California, San Francisco, San Francisco, California 94143, USA. jhong.md@gmail.com
Background:
Although the use of endoscopes and image guidance provide some safeguards, motility complications from orbital injury during endoscopic sinus surgery still pose a significant concern and can provide a therapeutic challenge.
Methods:
We present the case of a 40-year-old woman with strabismus secondary to an iatrogenic injury to the medial rectus muscle during endoscopic sinus surgery.
Results:
Permanent resolution of diplopia was achieved with botulinum toxin A injection into the lateral rectus muscle without the need for surgical intervention.
Conclusion:
Botulinum toxin A should be considered as a first-line early therapeutic option for cases of iatrogenically induced strabismus after endoscopic sinus surgery when complete transection or entrapment is not present.
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